Cholesterol homeostasis is maintained through concerted action of the enforcer wave to open SREBPs and LXRs.Here, we report that RNF145, a previously uncharacterized ER membrane ubiquitin ligase, participates in crosstalk between these critical signaling pathways.RNF145 expression is induced in response to LXR activation and high-cholesterol diet f
This study shows the great potential of pearl millet flour (MF) for producing nutrient dense enforcer wave to open and acceptable gluten-free (GF) bread, which is an innovation considering the actual commercial reality.This research highlights the use of design of experiments and multivariate analysis to determine the proper MF and water (W) levels
soderhamn ottoman cover Background: This randomized split-mouth study aimed to evaluate the feasibility of ultrawide immediate implants in fresh extraction sockets of nonrestorable molars.The comparison was made with standard-diameter implants placed in healed ridges of missing molars.After 1 year of functional loading, both groups were assessed fo
Celiac disease (CD) is an autoimmune disorder triggered by gluten in genetically susceptible individuals characterized by a variable combination of gluten-dependent symptoms, presence of specific autoantibodies and enteropathy.The health burden of CD is considerable, as it reduces quality of life and, at a societal level, has extensive negative eco